Exercises marked with (*) require further reading/search beyond the suggested texts.
3. BLAST the following amino acid sequence and find out whether it aligns with a continuous stretch of some important protein.QQLEDLKGYLEWITQAE
Answer:
Program used: protein blast (blastp).
After running the program with the amino acid sequence (the alignment is attached to this message), the results pointed to the following protein: voltage-dependent L-type calcium channel subunit alpha-1C-like.
Voltage-dependent calcium channels (VDCC) are a group of voltage-gated ion channels found in the membrane of excitable cells, like muscles and neurons, with a permeability to the calcium ion Ca2+.
References:
NCBI Blast Tutorial
Blast
Wikipedia - Voltage-dependent calcium channel
Wikipedia - Voltage-gated ion channel
Wikipedia - List of proteins
© 2015 Joao Meidanis