MO640 - Exercises - DNA Evolution Models, Durand-lec-notes (2014), Felsenstein (2004)- chapters 11 and 13

Exercises marked with (*) require further reading/search beyond the suggested texts.

1. Two 41-character long DNA sequences differ in 6 positions. Admitting that their evolution follows the Jukes-Cantor model, what is the Jukes-Cantor distance between them?

Answer:

The Jukes-Cantor distance can be calculated by the formula

Jukes-Cantor distance formula

where K is the genetic distance and d is the number of observed substitutions divided by the sequence length. The Jukes-Cantor distance between the two sequences is:

0.1628


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