MO640 - Exercises - Algebraic theory, Feijao and Meidanis 2013

Exercises marked with (*) require further reading/search beyond the suggested texts.

1. Write in algebraic form as a product of disjoint permutation cycles the reversal involving blocks B and C of the linear chromosome below.

chromosome with A, -B, C, D

Answer:

From the image above, we write π in adajcency algebraic form:

π = (-A -B) (B C) (-C D)

We wish to reverse blocks B and C by multiplying π by an operation ρ, so we need:

ρπ = (-A -C) (B C) (-B D)

We now discover ρ by solving:

(A -C) (B C) (-B D) = ρ (-A -B) (B C) (-C D)

If we multiply a given genome π, in algebraic form, by its inverse, we obtain the identity. Therefore, the equation x = y (A B) is equivalent to x (A B) = y. Applying this reasoning several times in the equation above, we get:

(-A -C) (B C) (-B D) = ρ (-A -B) (B C) (-C D)
(-A -C) (B C) (-B D) (-C D) = ρ (-A -B) (B C)
(-A -C) (B C) (-B D) (-C D) (B C) = ρ (-A -B)
(-A -C) (B C) (-B D) (-C D) (B C) (-A -B) = ρ

Lastly, we simplify ρ so that it becomes a product of disjoint cycles:

ρ = (A) (-A D) (B) (-B -C) (C) (D -A) (-D)

Which is the same as:

ρ = (-A D) (-B -C)

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