LOCUS       HSAPOAIA     2209 bp    DNA             PRI       03-NOV-1994
DEFINITION  Human fetal gene for apolipoprotein AI precursor.
ACCESSION   X01038
NID         g28769
KEYWORDS    apolipoprotein; signal peptide.
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Seilhamer,J.J., Protter,A.A., Frossard,P. and Levy-Wilson,B.
  TITLE     Isolation and DNA sequence of full-length cDNA and of the entire
            gene for human apolipoprotein AI--discovery of a new genetic
            polymorphism in the apo AI gene
  JOURNAL   DNA 3 (4), 309-317 (1984)
  MEDLINE   85026665
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
     TATA_signal     8..13
     mRNA            join(39..56,254..316,504..660,1249..1907)
     exon            39..56
                     /number=1
     intron          57..253
                     /number=1
     exon            254..316
                     /number=2
     sig_peptide     join(274..316,504..514)
     CDS             join(274..316,504..660,1249..1852)
                     /codon_start=1
                     /product="apolipoprotein AI precursor"
                     /db_xref="PID:g296635"
                     /db_xref="SWISS-PROT:P02647"
                     /translation="MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVD
                     VLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKE
                     TEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHE
                     LQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHA
                     KATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ"
     intron          317..503
                     /number=2
     exon            504..660
                     /number=3
     mat_peptide     join(515..660,1249..1849)
                     /product="apolipoprotein AI"
     intron          661..1248
                     /number=3
     exon            1249..1907
                     /number=4
BASE COUNT      450 a    688 c    685 g    384 t      2 others
ORIGIN      
        1 ctgcagacat aaataggccc tgcaagagct ggctgcttag agactgcgag aaggaggtgc
       61 gtcctgctgc ctgccccggt cactctggct ccccagctca aggttcaggc cttgccccag
      121 gccgggcctc tgggtacctg aggtcttctc ccgctctgtg cccttctcct cacctggctg
      181 caatgagtgg gggagcacgg ggcttctgca tgctgaaggc accccactca gccaggccct
      241 tcttctcctc caggtccccc acggcccttc aggatgaaag ctgcggtgct gaccttggcc
      301 gtgctcttcc tgacgggtag gtgtccccta acctagggag ccaaccatcg gggggccttc
      361 tccctaaatc cccgtggccc accctcctgg gcagaggcag caggtttctc actggccccc
      421 tctcccccac ctccaagctt ggcctttcgg ctcagatctc agcccacagc tggcctgatc
      481 tgggtctccc ctcccaccct cagggagcca ggctcggcat ttctggcagc aagatgaacc
      541 cccccagagc ccctgggatc gagtgaagga cctggccact gtgtacgtgg atgtgctcaa
      601 agacagcggc agagactatg tgtcccagtt tgaaggctcc gccttgggaa aacagctaaa
      661 gtaaggaccc agcctggggt tgagggcagg ggcagggggc agaggcctgt gggatgatgt
      721 tgaagccaga ctggccgagt cctcacctaa tatctgatga gctgggcccc acagatggtc
      781 tggatggaga aaccggaatg gatctccagg cagggtcaca gcccatgtcc cctgcaaagg
      841 acagaccagg gctgcccgat gcgtgatcac agagccacat tgtgcctgca agtgtagcaa
      901 gcccctttcc cttcttcacc acctcctctg ctcctgccca gcaagactgt gggctgtctt
      961 cggagaggag aatgcgctgg aggcatagaa gcgaggtcct tcaagggccc actttggaga
     1021 ccaacgtaac tgggcaccag tcccagctct gtctcctttt tagctcctct ctgtgcctcg
     1081 gtccagctgc acaacggggc atggcctggc ggggcagggg tgttggttga gagtgtactg
     1141 gaaatgctag gccactgcac ctccgcggac aggtgtcacc cagggctcac ccctgatagg
     1201 ctggggcgct gggaggccag ccctcaaccc ttctgtctca ccctccagcc taaagctcct
     1261 tgacaactgg gacagcgtga cctccacctt cagcaagctg cgcgaacagc tcggccctgt
     1321 gacccaggag ttctgggata acctggaaaa ggagacagag ggcctgaggc aggagatgag
     1381 caaggatctg gaggaggtga aggccaaggt gcagccctac ctggacgact tccagaagaa
     1441 gtggcaggag gagatggagc tctaccgcca gaaggtggag ccgctgcgcg cagagctcca
     1501 agagggcgcg cgccagaagc tgcacgagct gcaagagaag ctgagcccac tgggcgagga
     1561 gatgcgcgac cgcgcgcgcg cccatgtgga cgcgctgcgc acgcatctgg ccccctacag
     1621 cgacgagctg cgccagcgct tggccgcgcg ccttgaggct ctcaaggaga acggcggcgc
     1681 cagactggcc gagtaccacg ccaaggccac cgagcatctg agcacgctca gcgagaaggc
     1741 caagcccgcg ctcgaggacc tccgccaagg cctgctgccc gtgctggaga gcttcaaggt
     1801 cagcttcctg agcgctctcg aggagtacac taagaagctc aacacccagt gaggcgcccg
     1861 ccgccgcccc ccttcccggt gctcagaata aacgtttcca aagtgggaag cagcttcttt
     1921 cttttgggag aatagagggg ggtgcgggga catccggggg agcccgggag gggcctttgg
     1981 ccctggagca gggacttcct gccggatctc aacaactccg tgcccagact ggacgtctta
     2041 gggccaagat cgacgttgga ggacctgctg gacgcntggc tgcttacgag tgagggagta
     2101 gagtctgcct tagcaaggct caagtagaaa ggaagtcaca gcggacnagg caaagccaca
     2161 gacaatccaa ggccaggtgc cctgaaaggg gctcaaacaa ggcctgcag
//