LOCUS HSEOTAX 5533 bp DNA PRI 30-SEP-1997 DEFINITION H.sapiens eotaxin gene. ACCESSION Z92709 NID g2462477 KEYWORDS eotaxin gene. SOURCE human. ORGANISM Homo sapiens Eukaryotae; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 39) AUTHORS Hein,H., Schluter,C., Kulke,R., Christophers,E., Schroder,J.M. and Bartels,J. TITLE Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene JOURNAL Biochem. Biophys. Res. Commun. 237 (3), 537-542 (1997) MEDLINE 97445071 REFERENCE 2 (bases 1 to 5533) AUTHORS Hein,H. TITLE Direct Submission JOURNAL Submitted (06-MAR-1997) Hein H., Christian-Albrechts-Universitaet zu Kiel, Dermatology/Hautklinik, Mol.Biol.Lab.609, Schittenhelmstr. 7, Kiel, Schleswig-Holstein, D-24105, Germany REMARK Revised by author 23-JUN-97 FEATURES Location/Qualifiers source 1..5533 /organism="Homo sapiens" /db_xref="taxon:9606" /tissue_type="lung" /cell_type="fibroblast" TATA_signal 3116..3121 exon 3159..3290 /number=1 mRNA join(3159..3290,4502..4613,4992..5533) gene 3215..5097 /gene="eotaxin" CDS join(3215..3290,4502..4613,4992..5097) /gene="eotaxin" /codon_start=1 /db_xref="PID:e329504" /db_xref="PID:g2462478" /translation="MKVSAALLWLLLIAAAFSPQGLTGPASVPTTCCFNLANRKIPLQ RLESYRRITSGKCPQKAVIFKTKLAKDICADPKKRWVQDSMKYLDQKSPTPKP" intron 3291..4501 /gene="eotaxin" /number=1 exon 4502..4613 /gene="eotaxin" /number=2 intron 4614..4991 /gene="eotaxin" /number=2 exon 4992..5533 /number=3 BASE COUNT 1507 a 1320 c 1140 g 1531 t 35 others ORIGIN 1 sncmgagtca gatacaggga armcssccmg ggggvgcybc ccggggggac acccsgggat 61 actttttarg ycttgggggg ttyssccccc yttkmtttgm ccgcgatttt tktgatgccc 121 cgcmrggggg gsggagccyt wkggaaaaac gccagcaacg gggccttttt avggkbcctg 181 gccttttgbt ggcyttttgc ctcacatgtt ctttcctgcg ttatcccctg attctgkgga 241 taaccgtatt accgcctttg agtgagctga taccgctcgc cgcagccgaa cgaccgagcg 301 cagcgagtca gtgagcgagg aagcggaaga gcgcccaata cgcaaaccgc ctctccccgc 361 gcgttggccg attcattaat gcagctggca cgacaggttt cccgactgga aagcgggcag 421 tgagcgcaac gcaattaatg tgagttagct cactcattag gcaccccagg ctttacactt 481 tatgcttccg gcccgtatgt tgtgtggaat tgtgagcgga taacaatttc acacaggaaa 541 cagctatgac catgattacg ccaagctatt taggtgacgc gttagaatac tcaagctatg 601 catcaagctt ggtaccgagc tcggatccac tagtaacggc cgccagtgtg ctggaattca 661 ggctctaata cgactcacta tagggcgtcg actcgatcaa ggcccctcat tcatcaggca 721 ccaaatcaca ggcaagaaat tggtctactc tacttcattg ctgaaaagaa agcctccaag 781 aaagaaagag aaaaagccct tgaagctgcc cctgcttgct agggatggcc agtgagctgg 841 atgaaacagc tgcagagctt ggatatctaa agattgattt tatttatttc cactgagcca 901 ctgaggtttt tcaggcgtag agtaaatcca aagcccatta actccaaagc cattttccaa 961 ggaaaacaca aaaatgaata atcgcttgct gataattcct ttaattcccg ccagagttat 1021 gaaattattc ttactacaga aacaatcatt aaaccacgtc agacaaacac ctctgaggac 1081 aataatattc ccaaatttat tctgccgaga attttttaaa acttcgtatc tgccacatgt 1141 gcaactcagg cattcttgga aaccatccct gcggtagcat atctttactt ggaagcagtg 1201 ggaaaacttg gaagaatatt tggagaaata tccagactct gaggtctttc caacattccc 1261 aatctgccct tctttttttt tttttttgag acacagtctc actctgttgc ccaggttgga 1321 gtgcagtggc atgatctctg cccattgcaa cctttgtccc ctgtgttcaa gcaattctca 1381 tgcctcagct tcctgagtag ctgagactac aaacaccatc caccatggct ggctaatttt 1441 ttgtattttt agtaaagaca ggttttcacc atgttgccca ggctggtctt gaactcctga 1501 cctcgagtga tctgcctgcc tcagtctccc aaagtgctgg gattacaagt gtgagccact 1561 gtacccggcc ctattcccta ataataaaaa acagtaactt ctactcactg agtatctaca 1621 gtgatttagt cattcttcta agcagtttag atacatgaac tcatttaatt cacacgacaa 1681 ttccctaaag tacacatgat tagtatcctg ctcttaccct agcagagagt ggttaagtaa 1741 gttgtccatg gtatcacagc tagtcagtca cagagccatc atccaaatgc agatatcctg 1801 aattcaggtt ctacattaga ctaacccacc gggaatggag caggaaagaa cagggaagac 1861 tccacatttt tggcctctat ttggtaatta tagttaactt tttaggtaat tatagaccaa 1921 ttatcctaga tgggcactta gagactttgc aggacagcaa gagctgtctc taatcctgtg 1981 cccatgacag acatcaccag tcaaccacaa cacagtattt aactaacgca agtcaactcc 2041 tcagaatctt taacatacct tgtttgtgct actgtaccaa tcaatcaatt tgatatgaga 2101 gtgtgcagga aaaaacagga aacaggtttg cagtacctcc acaccagtat tcaatgctgt 2161 aatccgctgc agtgactcca ttaaatactt tgcctccctt ataccctctc caactagggt 2221 gcctagtgtt atgaacaaag ggatatgtat aggttcttgt gttgcctctc tctttgatat 2281 ttttagccat cagatacctt gtctgcaatg tgtgctcaga gagtgagggg ggaactagat 2341 gattgatttt ccaaawtgtg tccctaaacg tgctccctgg ggaataaggg cacgagaggc 2401 tgcctattct atttcaaaca aatccccttc actacagtgt atttgatgag ttggggtttg 2461 ttttaattcc atttggaaaa gggctttagc agctaagcaa atggttttaa agtgcctcag 2521 aagtcaagat taatagaaac tatccagttc tgatgtccta tcatgctaaa atttcaggga 2581 ctaagattct gtgatcatta cattgaaaca cagcagcaaa gctgtggtgt gttgtccttc 2641 ctggttcaga gatgcaacta tgtgcagggc tgctgagctc tctctgcatc tgggtgggag 2701 cctaatggaa gttttggggc tccttactgg tctccaaaat cctcaagacc accatgtgaa 2761 cacaggaatc aaggaaggtt cttagatcga ctcatccccc aggcctttgg tttccttgct 2821 cctttccccg actacaggtg tttcatttca actcatcccc tagggccttg gttttcttgc 2881 tctcttcccc cactacagat gtttaacttc atttcataac cacatattcc cctccttttc 2941 caaggcaaga tccagatgga ttaaaaattg taccaagtcc ctcctactag tcttgcctct 3001 cttctgttct gcttgacttc ctaggatctg gaatctggtc agcaatcagg aatcccttca 3061 tcgtgacccc gcatgggcaa aggcttccct ggaatctccc acactgtctg ctccctataa 3121 aaggcaggca gatgggccag aggagcagag aggctgagac caacccagaa accaccacct 3181 tctcacgcca aagctcacac cttcagcctc caacatgaag gtctccgcag cacttctgtg 3241 gctgctgctc atagcagctg ccttcagccc ccaggggctc actgggccag gtaagccccc 3301 caactcctta caggaaaggt aaggtaacca cctccagagc tactaggtca gcaagaatct 3361 ttacagactc actgcaaatt ctccatttga aaaataggga aacaggtttt gtgggtggac 3421 aagaaatgcc tcaaccgtca catccagtca ctggaagagc cagaactaga aagctcccga 3481 gtcttttccc acattcaaga gggttgctgg gtgcatccat acccagctat ccttacagtg 3541 tttgggaatg gggaatggct ctgtcttact gtgggcatgg tgggcatttt tggcagtggg 3601 agagaaggaa aatctgttga ttagaagctc agtatgttaa ttcgactcca ggacagcttt 3661 cagagacagt ggctaagaga agaacgaggt cccaggggga tctcttgagg tgacttattt 3721 tgacactctt tgggaaagtt atctaggaga tttgttccat aactcatttt cccatactct 3781 ggtgacaaat ttactgagtg tatcggtccc actgagccag tgcatagcat ggtaacaaac 3841 agttctaaat tatcaatgac ttaacagaat taactaaatt aacaaaagtt actttctcac 3901 ttgtactaaa tatctataat gtatgggctc aggcttctgc attttatact caggattcta 3961 gactgatgga gaagttgccc atgtggggga acattgatgg atactgtgat aaagcagaag 4021 aaagctctca ggagtcttgc ataggcaatg cactgtggct caaaaatgac acccatcact 4081 ttgtctcctt ctttattgat caaaactaat taatgcctcc aaccaaacaa aagtggccaa 4141 gaaatgcaag tctaccttgt gtctcaaaac agaggatgga gaatatttgg tgaaaattac 4201 catgaccatc acatggccac gtaggtcttt ataatgacag agctagcatt tgtcacattg 4261 accaagcttt gtccatacac tctacagtaa tgatgagtcc tcagtgcaca ggggaggatg 4321 ctgaagacac aggacagcat cctccagaca cataagactt cagagcagag ggattctccc 4381 tccacctctc gcaattcctt gctttctcct aacttccttt acaaagtcat gcttggaaat 4441 gtctatgtat catcatgtgg ctcatttttt tctctgttca ctttttttcc ccaaaattca 4501 gcttctgtcc caaccacctg ctgctttaac ctggccaata ggaagatacc ccttcagcga 4561 ctagagagct acaggagaat caccagtggc aaatgtcccc agaaagctgt gatgtaagta 4621 aataaagttc accctcccct ggacaaaaaa ataatgtcta gggcacagag tcaagaactg 4681 tgtcacagtt gctgggagtc atagactctg atagtttgac ctctatggtc caattcatta 4741 attttcacaa gtgagtgttc actcccagct ccctgcctgg gagattgctg tagtcatatc 4801 aatttcttca agtcaagagc aaagatggtt ttactgggcc tttaagagca gcaactaacc 4861 caagagtctc atccttcctc ctctccgtag caaccctttg tccaggggca gatggtcctt 4921 aaatatttgg ggtcaaatgg gcagaatttt caaaaacaat ccttccaatt gcatcctgta 4981 tctccccaca gcttcaagac caaactggcc aaggatatct gtgccgaccc caagaagagg 5041 tgggtgcagg attccatgaa gtatctggac caaaaatctc caactccaaa gccataaata 5101 atcaccattt ttgaaaccaa accagagcct gagtgttgcc taatttgttt tcccttctta 5161 caatgcattc tgaggtaacc tcattatcag tccaaagggc atgggtttta ttatatatat 5221 atatatatat ttttttttaa aaaaaaacgt attgcattta atttattgag gctttaaaac 5281 ttatcctcca tgaatatcag ttacttttaa actgtaaagc tttgtgcaga ttctttaccc 5341 cctgggagcc ccaattcgat cccctgtcac gtgtgggcaa tgttccccct ctcctctctt 5401 cctccctgga atctttaaag gtcctggcaa agatgatcag tatgaaaatg tcattgttct 5461 tgtgaaccca aagtgtgact cattaaatgg aagtaaatgt tgttttagga atacataaag 5521 tatgtgcata ttt //