LOCUS HSHAP1 2957 bp DNA PRI 25-SEP-1992 DEFINITION H.sapiens HAP1 gene for AP endonuclease 1. ACCESSION X66133 NID g32021 KEYWORDS endonuclease I; HAP1 gene. SOURCE human. ORGANISM Homo sapiens Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata; Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2957) AUTHORS Robson,C. TITLE Direct Submission JOURNAL Submitted (01-JUN-1992) C. Robson, Imperial Cancer Res Fund, Mol Oncology Laboratory IMM, John Radcliffe Hospital, Headington, Oxford OX39 9DU, UK REFERENCE 2 (bases 1 to 2957) AUTHORS Robson,C.N., Hochhauser,D., Craig,R., Rack,K., Buckle,V.J. and Hickson,I.D. TITLE Structure of the human DNA repair gene HAP1 and its localisation to chromosome 14q 11.2-12 JOURNAL Nucleic Acids Res. 20 (17), 4417-4421 (1992) MEDLINE 93027134 FEATURES Location/Qualifiers source 1..2957 /organism="Homo sapiens" /db_xref="taxon:9606" /clone_lib="Lorist" exon <587..587 /number=1 intron 588..769 /number=1 exon 770..895 /number=2 gene 838..2699 /gene="HAP1" CDS join(838..895,1106..1293,1859..2051,2182..2699) /gene="HAP1" /codon_start=1 /product="AP endonuclease 1" /db_xref="PID:g32022" /db_xref="SWISS-PROT:P27695" /translation="MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPAL YEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSEN KLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVA EFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEI DLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSK NVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL" intron 896..1105 /gene="HAP1" /number=2 exon 1106..1293 /gene="HAP1" /number=3 intron 1294..1858 /gene="HAP1" /number=3 exon 1859..2051 /gene="HAP1" /number=4 intron 2052..2181 /gene="HAP1" /number=4 exon 2182..>2699 /gene="HAP1" /number=5 BASE COUNT 712 a 713 c 714 g 818 t ORIGIN 1 ctgcagatag cactgggaaa gacaccgcgg aactcccgcg agcgagaccc gccaaggccc 61 ctccagggac ctgtcttcct aacgtccagg gagcccgagc caactcgcgc cttacattcg 121 tatccgtttt cctatctctt tcccgtggtc agcccagcct tctccactgt ttttttcctc 181 ttgcacagag ttagaatctt aagtcagtgt cacacaatgt gctgtgcatc tggcacaacg 241 ataaacagcc gagggagggt tggggactaa gtgcctagag aattagagga gggaggcgag 301 gctaagcgtc cgtcacgtgg tgtcagacag accaatcacg cgcattcttc ggccacgaca 361 agcgcgcctc tgatcacgtg accaggtccg ctacccacgt gggggctcag cgtgcaccct 421 tctttgtgct cgggttagga ggagctaggc tgccatcggg ccggtgcaga tacggggttg 481 ctcttttgct cataagaggg gcttcgctgg cagtctgaac ggcaagcttg agtcaggacc 541 cttaattaag atcctcaatt ggctggaggg cagatctcgc gagtagggta caaggcacta 601 tgaaatgatc tagtttcgtg ggtgaggggc tgaagggcct atgatgcacg gaggcgggga 661 aaggatttag agataacgtg gtttaaaggc gggacctggt gcggggacgc tccttgggag 721 gagtcttctc ccagccttag ctggtttcat gatttctttg cgtctgtagg caacgcggta 781 aaaatattgc ttcggtgggt gacgcggtac agctgcccaa gggcgttcgt aacgggaatg 841 ccgaagcgtg ggaaaaaggg agcggtggcg gaagacgggg atgagctcag gacaggtaag 901 ggaatgaaat cagcccttct tcctagaagc tgcggcgggg gtgtttgtca ttcccttgat 961 gtacggtaag tacgggccga ctcatttttg caggggtttg tgaagaagtc gcaggaaccg 1021 taggctttcg ttgggtctat agttaacgcc ggatcgcagt tggaaaccac cagctttttg 1081 tcagtatata ttactcattt tatagagcca gaggccaaga agagtaagac ggccgcaaag 1141 aaaaatgaca aagaggcagc aggagagggc ccagccctgt atgaggaccc cccagatcag 1201 aaaacctcac ccagtggcaa acctgccaca ctcaagatct gctcttggaa tgtggatggg 1261 cttcgagcct ggattaagaa gaaaggatta gatgtgagtg gaatttgagg gaaagagaca 1321 ttttttagta ttgaatggtc ttagggttta gtcacccctt ttctccgttt agccttcagg 1381 ctgttttatt tttctcctgc ccgtagtttt ctgtggggct tccccagtct tgccagttgt 1441 atttcctaaa tgtctgttcc ttcacttcca ttgccatttt cttttttagt gttctctcct 1501 cttcccagaa tgttgcaaaa acctcttcac tatacttcct ccattttatc ttcctgcatt 1561 gcattccata tgaagcatgt cctccattcc attaaccata gcttaaaatc ttagcttgct 1621 atccactgcc tatagaaaaa acacatctcc ttggcatagc atgtaagact ttcttacctc 1681 tctatatttg ttttcattta tctagcttag aattgtttga atattgtgct gcttgactcg 1741 aactccttag gccaagagac tgtttaaccc gtgcgtatct atgacttagc atatagatta 1801 ttcaataaat gttctgctga attgataata cgttttccac ctttcttttc acttacagtg 1861 ggtaaaggaa gaagccccag atatactgtg ccttcaagag accaaatgtt cagagaacaa 1921 actaccagct gaacttcagg agctgcctgg actctctcat caatactggt cagctccttc 1981 ggacaaggaa gggtacagtg gcgtgggcct gctttcccgc cagtgcccac tcaaagtttc 2041 ttacggcata ggtgagaccc tattgatgcc taatgcctga actcttcaaa accaattgct 2101 aattctctat ctctgcccca cctcttgatt gctttccctt ttcttatagt tttttatgct 2161 aattctgttt catttctata ggcgatgagg agcatgatca ggaaggccgg gtgattgtgg 2221 ctgaatttga ctcgtttgtg ctggtaacag catatgtacc taatgcaggc cgaggtctgg 2281 tacgactgga gtaccggcag cgctgggatg aagcctttcg caagttcctg aagggcctgg 2341 cttcccgaaa gccccttgtg ctgtgtggag acctcaatgt ggcacatgaa gaaattgacc 2401 ttcgcaaccc caaggggaac aaaaagaatg ctggcttcac gccacaagag cgccaaggct 2461 tcggggaatt actgcaggct gtgccactgg ctgacagctt taggcacctc taccccaaca 2521 caccctatgc ctacaccttt tggacttata tgatgaatgc tcgatccaag aatgttggtt 2581 ggcgccttga ttactttttg ttgtcccact ctctgttacc tgcattgtgt gacagcaaga 2641 tccgttccaa ggccctcggc agtgatcact gtcctatcac cctataccta gcactgtgac 2701 accaccccta aatcactttg agcctgggaa ataagccccc tcaactacca ttccttcttt 2761 aaacactctt cagagaaatc tgcattctat ttctcatgta taaaactagg aatcctccaa 2821 ccaggctcct gtgatagagt tcttttaagc ccaagatttt ttatttgagg gttttttgtt 2881 ttttaaaaaa aaattgaaca aagactacta atgactttgt ttgaattatc cacatgaaaa 2941 taaagagcca tagtttc //