LOCUS       HSRPII145    2093 bp    DNA             PRI       07-DEC-1993
DEFINITION  H.sapiens gene for RNA polymerase II 14.5 kDa subunit.
ACCESSION   Z23102
NID         g397149
KEYWORDS    RNA polymerase II.
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2093)
  AUTHORS   Acker,J., Wintzerith,M., Vigneron,M. and Kedinger,C.
  TITLE     Structure of the gene encoding the 14.5 kDa subunit of human RNA
            polymerase II
  JOURNAL   Nucleic Acids Res. 21 (23), 5345-5350 (1993)
  MEDLINE   94089382
REFERENCE   2  (bases 1 to 2093)
  AUTHORS   Kedinger,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUN-1993) claude Kedinger, U184INSERM-LGME UPR6520
            CNRS-Inst.Chimie Biol.ULP, Strasbourg, 11, rue Humann, Strasbourg,
            Alsace, 67085, France
FEATURES             Location/Qualifiers
     source          1..2093
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /cell_line="HeLa cells"
     promoter        1..372
     exon            373..448
                     /number=1
     mRNA            join(373..448,533..587,834..907,996..1070,1181..1232,
                     1430..>1530)
     CDS             join(390..448,533..587,834..907,996..1070,1181..1232,
                     1430..1492)
                     /codon_start=1
                     /product="RNA Polymerase II subunit 14.5 kD"
                     /db_xref="PID:g397150"
                     /db_xref="SWISS-PROT:P36954"
                     /translation="MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDY
                     QQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSA
                     RAEDAMRLYYVCTAPHCGHRWTE"
     intron          449..532
                     /number=1
     exon            533..587
                     /number=2
     intron          588..833
                     /number=2
     exon            834..907
                     /number=3
     intron          908..995
                     /number=3
     misc_feature    930
                     /note="That base was not found in an independent allele.
                     The intron 3 can therefore be shorter by one base pair."
     exon            996..1070
                     /number=4
     intron          1071..1180
                     /number=4
     exon            1181..1232
                     /number=5
     intron          1233..1429
                     /number=5
     exon            1430..>1530
                     /number=6
BASE COUNT      386 a    653 c    627 g    427 t
ORIGIN      
        1 gagctcgccc agtccgcgaa gggtaaactc gcgcatgcgc actggccttc aaccaagcca
       61 agcgccttgg cttctgtcct ggatgctcag tgttttgcgg tttacgatgc gcatcgtttt
      121 cccggctctg gcaccagatc catactattc tgtaaactga ggcggcgatg cccaaaaatt
      181 ggaagcaatt actctaagat atcaaaagat tgaagcaagc catgaaacct ctgcgcggag
      241 agagccgagc ccgaggcggc ggggagccag caagtgtgcg cagctccgcc ctcttttggc
      301 gaagcaccta ggcctggccc ctcccgcgac ctgtagcgcg gcggagcaag cgcagaaggc
      361 tgggagggct gcgcgggctg cgcgtcgcca tggagcccga cgggacttac gagccgggct
      421 tcgtgggtat tcgcttctgc caggaatggt gaggcggagg gagcgggtga tgttagaagg
      481 cgggcgagga atggctccag gactaacccc tggcacctcc ccctccccac agtaacaaca
      541 tgctgtaccc caaggaagac aaggagaacc gcattctgct ctacgcggtg agcgccgggg
      601 tcttccccgg caggtccacc tgttcccagc gtggccccgc cctgccccct gcctctgtga
      661 tcggactccc tgttcgccct ccgctgcacc tcaagtgatc ctgactctca tgtcctgccc
      721 atccccaaag agagtcctgt cgtcatatcc tccgggatca ccctgccctc tcctcccaat
      781 cttgtctgga atccttccgt gacccccttt cccccacact cgccctctcg tagtgccgga
      841 actgtgatta ccagcaggag gccgacaaca gctgcatcta tgtcaacaag atcacgcacg
      901 aagtggagtg agtggcgggc cctgagctgg ggggcggggg tgttggctct ggaggctggg
      961 tctgagcgta attttgcacc cccgcgtccc tgcagcgaac tgacccagat tatcgccgac
     1021 gtgtcccagg accccacgtt gccgcggacc gaggaccacc cgtgccaaaa gtgagcgttc
     1081 agctggtact ggggaggtaa agtgaggctc gtctcctcac tgggcgaagg gaggagggaa
     1141 gggtgtgaag cctccggtga ccgagcccct accctctcag gtgcggccac aaggaggctg
     1201 tgttcttcca gtcacacagt gcgcgggccg aggtaagtgg cgcgagggct ttctaagtat
     1261 ctggggcttg tttggtcctt tctgggggcg gggatatcaa tgtgggtgac cctgcgcttc
     1321 ttggaactct gccgggccct tacctattgg tgaagttctc ttgcctgttc ttttggggta
     1381 aggcgctgct gggtccaaat ccttcctaac catgcatcat ttctgccagg acgccatgcg
     1441 cctttactac gtgtgcacag ccccacactg cggccaccgc tggaccgagt gacctcctct
     1501 ctcccccgag tgtaataaac accagattcc atgcgtgagt tttctgtgtt tatttgcctc
     1561 gtggggagga cgctggcaca ccgtatcagg ctgcgcggtg cagggcgcgg tgctgtgcgt
     1621 aggtgtcggg ccgggagctg gtgaagccgc agtcctcgca cacgtgcagc ttctcgcggc
     1681 gctcacggta agcgtagctg gcccggcctg tccatgcacc ttagcaaggt gagcttccag
     1741 ggagcagcgc tgcgtaaacg ctttcccgca agcactggag cggaagggcc ggatccctgc
     1801 acagatgggc gcagagggga gggctggaca gagagggcaa tgggctctgg actaaagcgc
     1861 ccccaccctg ctttccagtg gcgagcattt ctggtaccta ttccaagctc tacagactct
     1921 tccgcccatg acccaccatc tgctaccgac acccagtgga gacatgggac agacacctgt
     1981 gtctccactc tcccacacca ggatgctccc tcccctgggg gatggagagg gaggccttcc
     2041 cttgcctcgc gatctggagc ctgaatcgta taaccggcat ccgtctacac tct
//