LOCUS HUMATPSAS 18004 bp DNA PRI 01-MAY-1997 DEFINITION Human gene for ATP synthase alpha subunit, complete cds (exon 1 to 12). ACCESSION D28126 D14706 NID g559316 KEYWORDS ATP synthase alpha subunit. SOURCE Homo sapiens DNA. ORGANISM Homo sapiens Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 18004) AUTHORS Akiyama,S. TITLE Direct Submission JOURNAL Submitted (29-JAN-1994) to the DDBJ/EMBL/GenBank databases. Shuichi Akiyama, Showa University, School of Dentistry, Department of Biochemistry; 1-5-8 Hatanodai, Shinagawa, Tokyo 142, Japan (E-mail:sakiyama@dent.showa-u.ac.jp, Tel:03-3784-8163, Fax:03-3784-5555) REFERENCE 2 (bases 1 to 18004) AUTHORS Akiyama,S., Endo,H., Inohara,N., Ohta,S. and Kagawa,Y. TITLE Gene structure and cell type-specific expression of the human ATP synthase alpha subunit JOURNAL Biochim. Biophys. Acta 1219 (1), 129-140 (1994) MEDLINE 94368840 FEATURES Location/Qualifiers source 1..18004 /organism="Homo sapiens" /db_xref="taxon:9606" repeat_unit complement(551..856) /rpt_family="Alu" repeat_unit complement(1341..1678) /rpt_family="Alu" repeat_unit 1921..2206 /rpt_family="Alu" misc_signal 2257..2268 /note="putative factor/enhancer sequence: Z-DNA" CAAT_signal 2399..2403 misc_signal 2423..2430 /note="CS1" misc_signal 2425..2430 /note="putative factor/enhancer sequence: PU BOX" CAAT_signal complement(2489..2494) misc_signal 2607..2614 /note="putative factor/enhancer sequence: SV40 enhancer core" misc_signal 2680..2687 /note="putative factor/enhancer sequence: AP-2" misc_signal 2790..2798 /note="putative factor/enhancer sequenec: GFII/MLTF" misc_signal 2807..2815 /note="putative factor/enhancer sequence: Mt4-like sequence" misc_signal 2823..2830 /note="CS2: nuclear factor-binding site" misc_signal 2852..2862 /note="putative factor/enhancer sequence: OX BOX-like sequence" misc_signal 2863..2871 /note="putative factor/enhancer sequence: Sp1" misc_signal 3055..3062 /note="putative factor enhancer sequence: AP-2" misc_signal 3090..3097 /note="putative factor/enhancer sequence: GFII-like sequence" misc_signal 3101..3107 /note="putative factor/enhancer sequence: GCF" misc_signal 3109..3119 /note="putative factor/enhancer sequence: NRF-2-like sequence" misc_signal 3152..3159 /note="putative factor/enhancer sequence: Mt3-like sequence" misc_signal 3165..3172 /note="putative factor/enhancer sequence: Mt1-like sequence" misc_feature 3252..3269 /note="G+C rich region" misc_signal 3283..3290 /note="putative factor/enhancer sequence: AP-2" misc_signal 3295..3302 /note="putative factor/enhancer sequence: EST-1" misc_signal 3303..3311 /note="putative factor/enhancer sequence: GFII" misc_signal 3310..3316 /note="putative factor/enhancer sequence: GCF" misc_signal 3342..3349 /note="initiator" 5'UTR 3355..3408 exon 3355..3468 /number=1 misc_signal 3367..3374 /note="CS3: nuclear factor-binding site" misc_signal 3388..3395 /note="putative factor/enhancer sequence: AP-2" CDS join(3409..3468,6478..6556,9759..9928,11614..11787, 11878..12044,13352..13500,14117..14268,14377..14601, 15115..15222,15352..15496,16954..17104,17245..17326) /standard_name="F1-ATPase alpha subunit" /codon_start=1 /evidence=experimental /product="ATP synthase alpha subunit" /db_xref="PID:d1006217" /db_xref="PID:g559317" /translation="MLSVRVAAAVVRALPRRAGLVSRNALGSSFIAARNFHASNTHLQ KTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGL KGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDG KGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGK TSIAIDTIINQKRFNDGSDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVS ATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGR EAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQ IFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFG SDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFE NAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFEA" transit_peptide join(3409..3468,6478..6546) misc_signal 3503..3510 /note="putative factor/enhancer sequence: AP-2" misc_signal 3526..3533 /note="putative factor/enhancer sequence: GCF" misc_signal 3555..3562 /note="putative factor/enhancer sequence: AP-2" misc_signal 3637..3642 /note="putative factor/enhancer sequence: CRE" misc_signal 3730..3735 /note="putative factor/enhancer sequence: GCF" misc_signal 3765..3772 /note="putative factor/enhancer sequence: AP-2" misc_signal 3809..3814 /note="putative factor/enhancer sequence: PU BOX" misc_signal 3952..3957 /note="putative factor/enhancer sequence: PU BOX" misc_signal 4168..4173 /note="putative factor/enhancer sequence: AP-3" misc_signal 4180..4188 /note="putative factor/enhancer sequence: C/EBP(AP-1)" repeat_unit complement(4632..4926) /rpt_family="Alu" repeat_unit complement(5118..5406) /rpt_family="Alu" repeat_unit 5488..5816 exon 6478..6556 /number=2 repeat_unit complement(6907..7211) /rpt_family="Alu" repeat_unit complement(7491..7807) /rpt_family="Alu" repeat_unit complement(8448..8746) /rpt_family="Alu" repeat_unit complement(9383..9708) /rpt_family="Alu" exon 9759..9928 /number=3 exon 11614..11787 /number=4 exon 11878..12044 /number=5 exon 13352..13500 /number=6 repeat_unit complement(13715..14010) /rpt_family="Alu" exon 14117..14268 /number=7 exon 14377..14601 /number=8 exon 15115..15222 /number=9 exon 15352..15496 /number=10 repeat_unit complement(15642..15975) /rpt_family="Alu" exon 16954..17104 /number=11 exon 17245..17458 /number=12 polyA_signal 17440..17445 polyA_site 17458 repeat_unit complement(17602..17901) /rpt_family="Alu" BASE COUNT 4525 a 3795 c 4072 g 5612 t ORIGIN 1 attacaggtg tgagccacca tgccggctaa ttttgttgtt attgttgttg ttgttttgag 61 atagtctcac tcctgtcgcg catactgaag tgcagaggcg caatcttggc tcactgcaac 121 ctccacctgg ctcactgcaa ccttcacctc ctgggttcaa gcgattctcc ttcctcagcc 181 tcctgagtag ctggggttac aggtgtgcac caccaccccc agctaatttt tgatttttta 241 gtagagacgg ggttttgcca tgttggccag gctggtcttg aactcctgac ctcaggcgat 301 ctgcctgcct tggcctccca atgtgctagg attacatgcg tgagccacca tgcccggcct 361 tgttgttttt agaaaccata ttttttcctg ttagcttgtg aaagttgatt gggtcattct 421 tgtcatcccc aactaaaaca gtgtcaagag gtaaagggaa aaaaaagcac tcagggcaca 481 taacattgct ccaaaaatgt aattatctgt aagcctggct gctgaaactg cccgctataa 541 cctaaaccag tttttttgtt tgtttgtttt gagatggagt ctcactctgt cgcccaggct 601 ggaatgcaat ggcatgattt tggctcactg caacctctgc ctccaggttc atgtgattct 661 cctgcctcag cctcccaagt agctgggatt acaggcaccc gccaacatac ccagccaatt 721 tttgtatttt tagcagagac ggggtttcat catgttggtc aggctggtct tgaactcctg 781 acctcaggtg atccacccgc ctcggcctcc caaagcgctg ggattacagg cgtgagccac 841 cgtgcctggc tgacctaaac cagttttatc taattagctg ctaaaaacaa cctgcagtga 901 ctctaagaat tgttttacct agttgccatt acttgccaat caaaacttgc cagctcccca 961 aaaccttact agtgacaatg aactttctta aagaacaata tacaacagtt ctcttttttt 1021 gttgtttgtt ttgatatagg gtcttgcttt gttgcccagg ctggagtgtt ccggtgtgat 1081 cacagctcac tgcactccca aactcctggg ctcaagtgaa cctctcatct tggcttccca 1141 acgtgttggg attacaggca tgagccactg ttcctggcta tatttctctt ttacaaaaat 1201 aaaacctcta accatctgtt tgttcttctg acgtaccaaa gaccaccctg tttgtgtgta 1261 tgccctgaat ggcaattatt gcttcccaaa tgttttaaat ttagagattt gtctctgtat 1321 tttattttac ttggacagcc tttttctttt tcttttcttt ttttctttct tttttttttt 1381 ttttttttag atggagtttc acttttattg cccaggctgg aggacagtgg tgcaatctgg 1441 ggctcactgc aacttctgcc tcccgggtta aagcaattct cctgcctcag cctccccagt 1501 agctgggatt acaggtgccc gcccccatgc ctggctaatt tttgtatttt tagtagagat 1561 ggggttttgc catgttggcc aagctggtct cgaactcctg acctcaggtg atccacccgc 1621 ctcagcctcc caaagtgctg ggattacagg cgtgagccac tgcgcctggc ttggacagcc 1681 tttttgtacc cctgattccc aggagaactg ctgctctatt ttcccatggc ttaccttgaa 1741 aagagtagga tactagagaa aaggatggct aatcacgtgt ttacaagcca tgtttcagga 1801 gatgaccctt gtagcccgga tatttatttg cctcaccaaa attcaggttc taggtgtaag 1861 ccaggatttg ggggatggaa ctgaaaatgc ttctccaaac ggtgaaaagc gggcccagcg 1921 cagaggctga ggaggaagga tcacttgaag ccaggagttc gagaccagcc tgggcaacat 1981 agagagacct ccccccacgc cctgcccacc accgccgtct ttacaaaaaa attagccagg 2041 catggtggtg ggaccacagg ggcacaggct gaggtcagag gattgctcca gcccaggagt 2101 tccaggctgc aatgaatggt gataaaccca ctgcactctt tcctgggcaa cagagtgaga 2161 ccctgtctta aataaaataa aataaataaa taaaaaaaaa agaaaagtga aggcaacgtt 2221 aataagtgtc cactatgaca taataataac cagcatcaca cacacacacg aatcttgcat 2281 atatcacaaa aatctcagta tggtaattct gtggagaaaa aaaaaaagcc catccaggta 2341 agcatagaaa gtgttttttc atcatctccc tttgactcca aatgaagaag cagagttccc 2401 aatagcatga actagatgtt ggcagaggaa aaagcgagtc ctcgtcctat cctggtgtaa 2461 acttctgatt ctggacaatt ctcagtagga ttggcaatga ctcttctagg cctccttgtg 2521 attgttgata tatttttttt aatttaaagt tccggaatac atgtccagga cgtgcaggtt 2581 tgttacacag gtaaatgtgt gccatggtgg tttgctgtaa ctatcatccc atcacctagg 2641 tattaagctc cgcatgtatt agctatttat cttgatgctc ccctcccccg gttatcagga 2701 tttttaaaca gtttgctcta attcactgac aggattcttt tagaatgaat ctaaaaaagc 2761 tgggaatctt taacctgagc gcagatcgga tcacgtggaa cggtgctggt gtttgttaaa 2821 aattcagatt gccccgaatt ttcgactcag agggtctgaa gtggggctaa gatctgcaga 2881 ttaacgggct ccgtgggagg ctccctgctg gtggccagtc ccggggttta gctgttcact 2941 gttgctactc gtgctaaacc acggtctaac actaccgaca ctattaatcg ccctggtcct 3001 caagacagcc gcgaccccag acgggtgagg ccctcatcct ctagcaccag atggggcctg 3061 ggaactgctg cttagcagat tcagctaccc acgtggtcac ccggggcaac cacaaggtcg 3121 actcaaaaga ccaaaataaa tgtataacga atgccaggac caaagccgga atatatctaa 3181 tcattcattt tgaggtttaa acttaaaaat gttacataaa aaaataagta acctgccaaa 3241 aaatgcagag tggcggcggg ggcgggggga gaggtggtga acgcgagggg cagtacttcc 3301 gggtcaggtg ggccggctgt cttgaccttc tttgcggctc ggccattttg tcccagtcag 3361 tccggaggct gcggctgcag aagtaccgcc tgcggagtaa ctgcaaagat gctgtccgtg 3421 cgcgttgctg cggccgtggt ccgcgccctt cctcggcggg ccggactggt gagcaccgaa 3481 ggccggcatg atgcaggcgg ccgggtgggg ctgcagggtg gtggtgcgcc ggctcgggcg 3541 ctctctgcag gagggcgagg ggctgtggga tgccgccatc ttgcacccgt ggcttctccg 3601 gctggacaga gcaggcgaca caggtgccct tttgctcgtc acctgcgcag aggcagaatg 3661 gtacagggca gacagttaac tcgatggtgt ccagagacag ggcctcaaga ttcctgcctt 3721 cggctgacag cggccctaga agggggatct tgggtgaagg tcagggcttg ggcgctagct 3781 ctccgaggcc tgttctgaat cggtgaggtt cctctctttc gattcttagg gtcgcgtccc 3841 gctgaaggtc agaaaactgc tgtcagctct tgttgaagct agtcagtgga gtctgacatt 3901 gtgtgaaggt cagcaggccc agcatttcac ctctgcctgg agctcagttt agaggaaagg 3961 aataaatgaa ggtggttttt ggaatactta cgtaggcttt ctcttagtgc tgaatacgaa 4021 acgaccgtga aaacgtcctg caggtgcaaa gaaccatttc atgtggccag cactgtgaca 4081 acagtgaagc tggtttctaa attgtctctc cggcagagtg tgtgctttgt ggcacttgga 4141 cgtgtttaaa gaatttgtcc ttgagttttc cacctggttt tgagtaattt ttagtgatgg 4201 agaattcaag taaaagagaa caaggttgga aaatggctgt aaggattaat acccttcgtt 4261 atttgtttcc cttgaaatta acatgatttc agtgtaaacg cattgacact gacacttttt 4321 ttttgttcta aaagtaatct caatttgaaa ggtgaaataa acatgttggc tgttttgctg 4381 ccttaacaac cgctggtagc atcttgggtt tctgttaaca aaaaagcatt tttaacggtt 4441 ttcatctagc tcttatggaa ggtagaggct tcagaattga cagtgaccag tcgcagtatt 4501 acaacttgaa ggagaaactg aaggaagttc caggtggctg caggatttgt tgagagagta 4561 aaataagtcc acatgccaca actcttggtt tctaatctaa ctctagcatt tattcagttt 4621 ttgtttgctt gttttttttt tttttttttt tttgagatgg tgtctcgctc agtcgcccag 4681 gctggactgc aatggcgtga tctccgccca ctgcaaccac cgcctcccag gatcaagtga 4741 ttctcccacc tcagcctccc gagtagctgg gattacaggc acccgccgtc atgccctgct 4801 actttttgta gtttttcgta gagacggggt ttcaccatgt tggctaggct ggtcttgaac 4861 tcctgacgtc aggtgatccg cccgcctcgg ccttctgaag tgctgggatt acaagcatga 4921 gccgtcgtgc ccggccgctt gttgtcgttg ttgttgttgt tgtttttaag aaaattggaa 4981 ctactttgag ttttgcccct tgtaggaagc tgtttatctt agaattcctg caactccatt 5041 aaaatacatc taaagtcaaa ataataaaaa ttgggtacct ttaaagggaa agacacttac 5101 attttgttaa cagttgcttt tttttttttt ttttgagacg gagttttgct tttgtcgccc 5161 aggctggagt gcagtggcgc gatcttggct caccacaacc tctgcctccc aggttcaagc 5221 gattctcctg cctcagcttc ccgagtagct gggattacag gcatgtgcca ccacgcccag 5281 ctaattttgt atttctagta gagacggggt ttctccatgt tggtcaggct ggtctccaac 5341 tcccgacctt aggtaatccg cccgccttgg cctcccaaag tgctgggatt acaggcatga 5401 gccaccgtgc cctgccaata gttgcttttt aaaatactga ctgccaggcc gggtgcagtg 5461 gctgacgtct gtaattccag cactttggga ggccaaggtg ggtgcatcac ctgaagtcag 5521 gagttcgaga tcaacctggc caacatggcg aaaccctgtc tctactaaaa ataaaaaaat 5581 tagccgggca tggtggtggt cgcctgtagt cccagctact caggaggccg aggcatgaga 5641 atcgcttgaa cctgggaggt gaaggttgca atgagccaag atcgtgcccc tgcactccag 5701 cttgggtgac agaatgagac tccgtctcag aaggaaaaaa aaaatgtgtg tgtatatata 5761 tatttactgc ccagtctggg caatatgatg aaatcctgtc tctataaaaa aaataagtac 5821 aaaaattagc ctggccaggt ggcgcactcc tgtgatccca cctactgggg aggctgaggt 5881 gggaggatca cctgagccca ggaagtcgag gctgtagtga gccgtgattg agccactgca 5941 ctccgacctg ggtgacaaga gtgagaccct gtcccaaaaa agaaaaaaaa ataagccggg 6001 tgcggtgctc acgcctatag ttctagcact ttgggaggcc aaggcgggtg gatcacttga 6061 ggtcaggagt tcgagaccag cctggccagc atggtgaaac cccgtctcta ctaaaaatat 6121 aaaaaattaa cctggtggag gtggcgcacc cctgtagtcc cagctactcg ggaggctgag 6181 aatcgcttga gactaggagg tggaggatgc agtgagccgt ctcaaaaaaa caataataat 6241 aaagtacaga ctgcatttta aaaatatgcg agtgtttact gtgtactagg agctgtataa 6301 aaggttttca catatatcaa aagctacttt cccatttgac attttaaaca aaatgcttta 6361 tatgtaatta gcattttcac cagtactttg atcacactaa gctggcattt gtttaagctt 6421 gtaagtttta taaaggcttt gttaaaaatc aaatttttaa gaatactttt gcactaggtc 6481 tccagaaatg ctttgggttc atctttcatt gctgcaagga acttccatgc ctctaacact 6541 catcttcaaa agactggtaa gttattattt ctcagtctac gccgcactta ctagatgaag 6601 atataaatta catacatcgt ataactgtgg tgagttgttt ttcatttgtt agttttttct 6661 ctagtttgta tagactctca ggttcttaaa ccatattgtt accatttagc cctgtcatgg 6721 ttctcttgtt atagtcaaat gaactactgt tacatatttt tcttttgata ttagtatggc 6781 ttctttgttc tggtaatggc ccttgggtag aaacagaaag aacatacact aggtaatgga 6841 atctttgtga cctctggaag acttcctttt tccttttcta aaaggcatta gaaaaaatgt 6901 aagttcttat tgataggttt tcttattctt tttctttttt tttgagacag aatcttgctc 6961 tgtcgccagg ctggagtgca gtggcaagat ctcggctcac tgcaacctct gtctcctgag 7021 ttcaagcaat tctactgcct cagtctcctg actagctggg attacaggca tgcaccacca 7081 tgcccggcta attttttgta ttttagtaga gacaaggttt caccatgttg gccaggatgg 7141 tctcgatctc ctgaccttgt gatatgcctg cctcggcctc ccaaagtgct gggattaaag 7201 gcgtgagcca ctgcaccggt ccactgatag gttttatttt ttcaaaggca gtagctacta 7261 gatatttggc aatctgtgaa cttgcacatt acagatgcag tagagaagtg gggaggcaag 7321 cataggaaga cactataagt tggggaattt ctttggagat gagtatttgg acttttaaaa 7381 taaaggttaa atatatatgt gtgtgagagt gtgtgtgtat atatgtgtgt gtgtgtgtgt 7441 gtgtgtgtgt gtgtgtatgt gtacacacac ccccacgttc agcatatatg tttttctttt 7501 ttcttttttt tttgagatgg agttttgctc ttgttgccca ggctggagtg cagtggcatg 7561 atctgggctc actgcagcct ctgcctcacg ggttcaagtg attctcctgc ctcagcctcc 7621 cgagtagctg ggattacagg tgcccaccac cacacccagc taatttttgt attttttgta 7681 gagacaaggt ttcaccatgt tagccaggct ggtctcgaac tcctgacctc aggtgatcca 7741 cctgccttgg cctcccaaag tggtgggatt acagacatga ggcactgtgc gtggcctcct 7801 tttttttgag actctgttgc ccaagctgga gtgcagttgc gccatctcag ctcactgcaa 7861 cctccacctc ccaggttcaa gtgattctcc tgagtcagct tccctagtgg ctaggattac 7921 aggcacgcac caccacacct ggctaatttt tgtattttta gtagagatag agtttcgcca 7981 tgttggcctg gctgatctca aagccctgac cccaggggat ccgtctacct tggcctccca 8041 aagtgctggg atgttttttt attttgtttt gttttgtttt ttgagacaga gtttcgctct 8101 gttgcccaag ctggggtgca gtagcgtagt cttggctcac tggaccctcc acctcctggg 8161 tttgagtgat tctctcctgc ctcagcctcc cgagtagctg gtattacaag catgcaccac 8221 cacagctggc tatttttttt tttttttttt ccttagtaga gatgggattt tgctgtgttg 8281 gccaggctgg tccaaactct tggcctcaag tggtccgccc gcctcccaaa gtgctggtat 8341 tactggcgtg agccactgca cccaacccct gtatgctaag atgaagaata ccacctatac 8401 taccctgtgt gccttgaaag agaaagacac actttgttaa cagttgattt ttatttttta 8461 ttttttattt ttttgagata gagtcttgct ctgtctccag gctggagtgc agtggggcta 8521 tctcagctca ctgcaacctc cttctcccag gttcaagtga ttctcgtgcc tcagccaccc 8581 aagtagctgg gattacaggc atgcaccacc atgcccggca aacttttgtg tttttagtag 8641 agatgggggt ttcaccatgt tgcccaggct ggtctcgaac tcctggcctc aagtgatcca 8701 ccccctttgg catcccaaag tgctggtttt acaggcatga tctaccgtgc ctggccaaca 8761 gttggttttt aaaatatgtt tttattgaat ttagccaaaa attcaggttt taacatagtt 8821 acagatttct tagaaattaa aggagaacat ttattttaag ggttttactt aatttgatta 8881 gcttcttgtc tggtttacat ttgttttgtg tggacttttt tttccttaat cacttggttt 8941 tattttcata gcttttaaaa atagaatctc gtgttacagt gtagaatata tatatataat 9001 ttttgtgtgt gtgatagtct cactttgtca cctatgctgg agtgcagtga cacaatcttg 9061 gcttactgtg acttccacct cccaggttca agcagttctt ctgtctcagc ctcctgagta 9121 gctgggacta caggcatgcc cgtgcccagc taattttttt tttattttta gtggagacgg 9181 ggtttcacaa tgttggccag gctggtctcg aactccttac ctcaagtgat ctgcctgcct 9241 cagcctccta aagtgctagc attaccactg tggctagcgt gagccactgt gctgggtctg 9301 tagaatatat ttggattatt atgatcacaa aactagtttt ttgttgttga gaaatgggct 9361 ttgaaaagat ccgaggacca gatttttatt attattatta ttattattat tattattatt 9421 attattattt tgagatggag tttttgccct tgttacccag gcttgagtgc aatggtgtga 9481 tttcagctca ccgcaacctc cgcctcctgt gttcaagcga ttcttctgcc tcagcctccg 9541 cctcccgagt agctgggatt acaggcatgt gccaccatgc ccagctaatt ttgtattttt 9601 agtagagaca gggttctcca tgttggtcag gctggtctca aactcctgcc cttaggtgat 9661 ctgcctgcct cagcctccaa aagtgctggg attacagctg tgagccactg tgcctggccc 9721 agattatttt tttaattgaa ttgaattgtc ttccataggg actgctgaga tgtcctctat 9781 tcttgaagag cgtattcttg gagctgatac ctctgttgat cttgaagaaa ctgggcgtgt 9841 cttaagtatt ggtgatggta ttgcccgcgt acatgggctg aggaatgttc aagcagaaga 9901 aatggtagag ttttcttcag gcttaaaggt aaattataaa ataagatttt ggtgttttag 9961 gatctaagtc ttctcagtta ttcatttagc gattcaaaga ttgtatcaga tttttaaaaa 10021 actttgtctt aatttgcctc agattttttt cttgttatta tcatagattg taaagagaat 10081 aaacttaagg gtttgaatta gccaagtttt tttactctag ggactgattt atacataact 10141 tgtagccact ggctccaaaa tataaaattg aataaacttt caccccaaat ccaagaagtt 10201 taagtctgtt ctgtcttgct gttaagatta ttttatacaa aagcaaagca tttgataact 10261 tcaacaaaat ttttctggtg gaaattggaa gtccgtgact ttgtatttct agtgagtaga 10321 catattgttc aaaggcgagt tttggtgtag ctatcagaag ctctctaatg taagtctact 10381 ttgtattggg ttgagcctca tctgtcaggg tatgagaaat aagttgtagg agttagggaa 10441 agcagaggat gacatctgga taaactagag agagtggaac tgtctagtag gcatgcagat 10501 atgggaaaag atagtcttga tactcttggt aatgtctact acggaaaaag agccacttga 10561 tgtggaagaa taattacaga gcccaaagtt atcattagct gtaagacatt ggccaattta 10621 gcatcttcag tgtacagtat ttatctttga aaggtgaggt cgaaacagat taattctgag 10681 ttcccctttt agcttttgaa atccaagtgt ctagaacagt actgtccagt agtattggaa 10741 atatgtagta ttctgcagtg atgagaatac atctgtgctg tttaatatgg tacctactat 10801 actatcacta ttaatcatgt aaaatgtggc tagtgtgaca ggaactgaat ttttaatctt 10861 ttaaatttga caaatttaaa tagccacatg tggttagtgg atgctgtatt gaacatcaga 10921 gatgtaggtt aaagtttttg gatgtgtaat gatattccat gatactccaa gtacttctcc 10981 agagttttca ttattgacca gactattcct ggaatagcct ttttgcttca gacatgattt 11041 aaagatctaa aatatagttt taatgatgag agatgatttg gtgctgttat gttatgaaaa 11101 tttgtatttg attggttaca gttaggtagc ttttaatttc actttctact aactcgaaga 11161 gtacaggttt tgattaattt ttgaaactgt ttatggagct tctcacacat aaataagatg 11221 ataatcaaat ttgtcttaag atttccattt ggccttcatc actttatttc atactgatca 11281 cccagcccaa gaatcattgc caaagaaaat acagtggaaa aaagcttatt aacctgtcca 11341 atttctttgc ttctgtaata gttatttgag gatatgatag tgagcatatt aggcttatca 11401 atgtgctgtc ctaagattat tcaaaatagc aattttaaaa gtcttaatca gagagggttg 11461 tttgttagtt ggaaaagtac tcaagaataa accaggtgaa aaggacaata ctgcttcccc 11521 ccccaccccc cgactatttt cttatgtagt attggtgtat ggggaggagt gcccattcag 11581 cttcattgat gttcaattgt gtcttttgtg cagggtatgt ccttgaactt ggaacctgac 11641 aatgttggtg ttgtcgtgtt tggaaatgat aaactaatta aggaaggaga tatagtgaag 11701 aggacaggag ccattgtgga cgttccagtt ggtgaggagc tgttgggtcg tgtagttgat 11761 gcccttggta atgctattga tggaaaggta ggtttaatgt tcgttagata tagttgcagc 11821 ttctaacaaa catcaaaact gattatgctt agggtttttc tttttatttt ttaacagggt 11881 ccaattggtt ccaagacgcg taggcgagtt ggtctgaaag cccccggtat cattcctcga 11941 atttcagtgc gggaaccaat gcagactggc attaaggctg tggatagctt ggtgccaatt 12001 ggtcgtggtc agcgtgaact gattattggt gaccgacaga ctgggtaaag actcaaaagc 12061 atattaaaag ttctaactaa aatttgctca atggaaggat tatattttag tcttggaatg 12121 gtaaatggta atggggacat tagaatctaa tacgaggatt aatagtaaaa tttcagctgg 12181 gaagtgaagg gggccagccc ctccacacct gtgggtattt ctcatcaggt gggacgagct 12241 agctcagtcg gtagagcatg ggactcttaa tcccagggtc gtgggtttga gccccatgtt 12301 gggcaccaga tgaagggggc cagcccctcc acacctgtga gtatttctcg tcaggtgggt 12361 tgagagactg agaaaataaa taagacacag agacaaagta tagagaaaga acagtgggcc 12421 caggggaacg gcgctcagca tatggaggac ccatgccgcc actggtctct gagttccctc 12481 agtatttatt gatcactatc tctactatct cggtgtgggg gatgtggcag gactgtaggg 12541 ttaatggtgg ggagagggtc agcaggaaaa cgtgagcaaa ggtctctgtg tcataaataa 12601 gtttaaggaa aggtgctgtg ccttgatgtg catgtaggcc agatttatgt ttgactttac 12661 acaaacatct cagtgcagta aagagcagta ttgctgccag catatctcac ctccagccat 12721 agggtggttt tctcctatct cagtaaatag aatgtacgat tgggttttac accaagacat 12781 tccattcccc gggacaagca ggagacagat gccttcatct tatctcaact gcaaagaggc 12841 tttcctcttt cactaatcct cctcagcaca gaccctttac gagtatcggg ctgggggatg 12901 gtcaggtctt tcccttccca cgaggccata tctcaggctg tctcagtggg gagaaacctt 12961 gcacaatacc caggctttat tgggcagagg gccctgcagc cttccacagt gcattgtgtc 13021 cctgggtact cgagactgga gaatggcgat aacttttacg aagtatactg cctgcaaaca 13081 catttttacc aaagcacatc ctgcacagcc ctaaatccgt taaaccttaa gtcaacacag 13141 cacatgtttc tgcgagcaca gggttggggc tatggttaca gactaacagc atctcaaggc 13201 agaagaattt ttcttagtac agaacaaaat ggagtttctt atgtcttctt ctttctgcat 13261 agacacagta acagtctgat ctctctttct ttccccacag ggaagtcctt ttaagtttag 13321 gaagatttat atttactttc tctttttaaa ggaaaacctc aattgctatt gacacaatca 13381 ttaaccagaa acgtttcaat gatggatctg atgaaaagaa gaagctgtac tgtatttatg 13441 ttgctattgg tcaaaagaga tccactgttg cccagttggt gaagagactt acagatgcag 13501 gtattaaaag aaatttagtc ccattgctat tatcttaagt cccattgctg ctgattgtag 13561 aatagcttct acttaatgaa ggcatatttt aattacttcc taatgggctg aactttttaa 13621 tacaaatcag taggtaagac aatgtaaaac agtagtacat ttaaaggttt tgttggtttc 13681 tttaaagtgg aagctgtttg attctgatta actctttttt tgttgtttga gacggagttt 13741 cactcttgtt gcccaggctg gagtgcgatg gcacgatctc agctcactgc aacctctgcc 13801 tcctgggttc aagcgattct cctgtctcag cctcccgagt agctgggatt acaggtgcat 13861 gccaccacgt ccggctaatt tttgtatttt tagtagagac ggagtttcct catattggtc 13921 aggctggtct cgaactcctg acctcaggtg atcacccgcc tagggcctcc caaagtgctg 13981 ggattacagg catgagccac tgcgcctggc ctgattaact cttaatggta aatattttta 14041 gcacttaggt aatttttata gtagcctcca atttaaaacc acaatattga taaaattgta 14101 aaatatattt tctcagatgc catgaagtac accattgtgg tgtcggctac ggcctcggat 14161 gctgccccac ttcagtacct ggctccttac tctggctgtt ccatgggaga gtattttaga 14221 gacaatggca aacatgcttt gatcatctat gacgacttat ccaaacaggt caaaggaaat 14281 aaatttttag aatccattta tttgtactga agtaaaagtt cacatatgca acttctattt 14341 aataggttaa cttcacaaac ctattctgta ccataggctg ttgcttaccg tcagatgtct 14401 ctgttgctcc gccgaccccc tggtcgtgag gcctatcctg gtgatgtgtt ctacctacac 14461 tcccggttgc tggagagagc agccaaaatg aacgatgctt ttggtggtgg ctccttgact 14521 gctttgccag tcatagaaac acaggctggt gatgtgtctg cttacattcc aacaaatgtc 14581 atttccatca ctgacggaca ggtattattt taatgattaa aagaaatgtt aaaaaagatt 14641 tggataattc taaggcattg gttgagacta atggtatatt gactgatttg ctaaatgcat 14701 tttacttttt attatggaaa atttcaaata catagaaaag ttaggagaat ggcatagtga 14761 aaccccatgt atctgtcacc cagttattgc atagagtagc atgtttcgtt ctagtttcat 14821 ttttaaccac tactgttctc ccttctagat aattttgaat caaatagaaa ttatatcact 14881 tcatttgtat gtatttcagt ataaatatgt tgcctattat gtttttttct catctcatgc 14941 acatctccta attgcagcaa taaaatatac aggtcaggtc gtgaaagatt tggggtactg 15001 atgctttgca ttgttaggtt ttgagtttca gctttttggc ataatgactt aaatttgaag 15061 atagttgatt tcttacttta agcttgctag cgtgcgtatt tccttacatt atagatcttc 15121 ttggaaacag aattgttcta caaaggtatc cgccctgcaa ttaacgttgg tctgtctgta 15181 tctcgtgtcg gatccgctgc ccaaaccagg gctatgaagc aggtaatttt gcatcacttt 15241 ggcagtaagg gggctatcat tagattagca tcttaaggta ttaatatatt aactatattt 15301 gtatagtgct ctgtgtcact gagttacagt acagtaattt ctgtattgca ggtagcaggt 15361 accatgaagc tggaattggc tcagtatcgt gaggttgctg cttttgccca gttcggttct 15421 gacctcgatg ctgccactca acaacttttg agtcgtggcg tgcgtctaac tgagttgctg 15481 aagcaaggac agtattgtaa gttgttcttt tcttcatttg gtcaggttcc tattgtgtat 15541 cagggtcttc ccaggcctac agagctgcat cacatatcac ggcctgtact acgtgttgtt 15601 atctgttatc tttcatcaaa ggcactttta cttaaactac atttgttttt tgatttttga 15661 tttttttttt tttttgagac gaagtttcat tcttacggcc taggctgaag tgcaatggcg 15721 caaccttggc tcattgcaac ctccacctcc tggattcacg cgattctcct gcctcagcct 15781 ccttagtagc tcggattaca ggtgtgagcc accacgcccg actaattttt gtatttttag 15841 tagagacagg gtttcaccat gttggccagg ctggtctcga actcctgacc tcaggtaatc 15901 caccctgcct cagcctccca aagtgctggg attacaggtg tgagccccca tgcccggccc 15961 tgtattctgt tttttaaaga gagacagtgt cttgcagtgt cacccaggct ggagtgcagt 16021 ggtgccatca tagctcactg caggcttgaa ctcctgggct caagcagtcc tgcagcctta 16081 gcttcctgag tagctaagac tacgggcatg cactaccatg cctggctaat ttttttgtat 16141 tttgtagaga cagggtctca ctatgttgcc caggctggtc ttgaactcct ggccttatgc 16201 catcttccca cctctcaaag tgctggcatt ataggcgtga gccaccatgc ccggcctcaa 16261 actatctttc tttttctttc tttctttttt tttttttttt ttaatacaga gtctccttct 16321 gtcacccagg ctggagtata tttttagtag aaatggtaaa acctctacca ttttggccag 16381 gctgatcttg aacccctgac cttaagtggt ccacccgcct cagagtccta aagtgctggg 16441 attacaggtg tgagttacca tgcccggccc aaactacatt tcttattatc atttgagtgt 16501 aaatgatagg ggcttcacaa ccaggaaaac ttaagtatat ttaatgtcct tctttcagga 16561 attaaggcct gttagagtcc cctcccccac ttggctatat gaatatgtaa tttggcagat 16621 ttaaaagaaa gttaatacgt ttttattttg tcaagtcatt tcagcaaaat atttatactc 16681 aaaacagtat taacactgtc agattataaa cagtgcttat ggctatactg aaagattatg 16741 cctcaagcct tgaaaatata agaaataact gttttctgtc aggggtggga ggaaggatta 16801 ttaagtggag ttctaggtca ttgatattgt gaagaataga taatttacag ggacatgtta 16861 ggaattggag aaaaagtaag ttttcctgac cttggtaaca tggcattcat ttctttgagc 16921 aactcacttg gcattcttct tgtatctttt cagctcccat ggctattgaa gaacaagtgg 16981 ctgttatcta tgcgggtgta aggggatatc ttgataaact ggagcccagc aagattacaa 17041 agtttgagaa tgctttcttg tctcatgtcg tcagccagca ccaagccttg ttgggcacta 17101 tcaggtatga atgcaattgt tggcatcttt ttttaaagtt atgtttaaga tatgaagtta 17161 aaattatttt caaatctgta gttaggctag tcattaaaac tttttccagg tcagaactta 17221 cgacctgctt ttatttccaa atagggctga tggaaagatc tcagaacaat cagatgcaaa 17281 gctgaaagag attgtaacaa atttcttggc tggatttgaa gcttaaactc ctgtggattc 17341 acatcaaata ccagttcagt tttgtcattg ttctagtaaa ttagttccat ttgtaaaagg 17401 gttactctca tactccttat gtacagaaat cacatgaaaa ataaaggttc cataatgcat 17461 agttgttttc tgtcatttgt gttattcttt aaaaccaaga tcaaattgag aaattggtaa 17521 gcaaatgctt cttgatctat tttacttgaa tattggtaca gtcaactggg ctagataatt 17581 caaggctgag ctctttgtaa gttttttttt tttttttttt ttttgagact gattctcact 17641 ctgtcactga ggctggagtg cagtggcacc ctgtcggccc actgcaacct ccgtctccgg 17701 gttcaagcaa ttctcttgcc tcagcctccc acgtagctgg gattacaggt gcccaccacc 17761 acgcctggct agttttttag tatttttagt agagacgggg tttcaccatg ttggccaggc 17821 cggtcacgaa ctcctgacct caggtgatcc acctgccttg gcctacctac cacagtgctg 17881 ggattacagg tgtgagccac cacacccggc tgctctttgt aagtttctag agtactttgt 17941 gtttaagaga aattcctaaa ctggaatatg tggcaggctg acaatactga agaggatagc 18001 tggc //